P387-1117 Screening compound: 1-phenyl-N-[2-(piperidin-4-yloxy)pyridin-3-yl]cyclopropane-1-carboxamide

P387-1117 Screening compound: 1-phenyl-N-[2-(piperidin-4-yloxy)pyridin-3-yl]cyclopropane-1-carboxamide
P387-1117 Screening compound: 1-phenyl-N-[2-(piperidin-4-yloxy)pyridin-3-yl]cyclopropane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P387-1117
1-phenyl-N-[2-(piperidin-4-yloxy)pyridin-3-yl]cyclopropane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P387-1117

Molecular Formula

C20H23N3O2 (C20 H23 N3 O2)

Compound Name

1-phenyl-N-[2-(piperidin-4-yloxy)pyridin-3-yl]cyclopropane-1-carboxamide

IUPAC name

1-phenyl-N-[2-(piperidin-4-yloxy)pyridin-3-yl]cyclopropane-1-carboxamide

SMILES

O=C(C1(CC1)c1ccccc1)Nc(cccn1)c1OC1CCNCC1

InChI

InChI=1S/C20H23N3O2/c24-19(20(10-11-20)15-5-2-1-3-6-15)23-17-7-4-12-22-18(17)25-16-8-13-21-14-9-16/h1-7,12,16,21H,8-11,13-14H2,(H,23,24)

InChI Key

OENIOSKWKGYEPE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996226

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

337.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.749

Distribution Coefficient, logD

-1.241

Water Solubility, LogSw

-2.06

Polar Surface Area

51.103

Acid Dissociation Constant (pKa)

10.03

Base Dissociation Constant (pKb)

10.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

P387-1117 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Nervous system
  • Cardiovascular
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Others
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P387-1117 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P387-1117?
Check Price and Availability of P387-1117, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P387-1117 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P387-1117
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P387-1117
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P387-1117 available by request