P392-0497 Screening compound: 2-(4-fluorophenoxy)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

P392-0497 Screening compound: 2-(4-fluorophenoxy)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one
P392-0497 Screening compound: 2-(4-fluorophenoxy)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P392-0497
2-(4-fluorophenoxy)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P392-0497

Molecular Formula

C23H26FN3O4 (C23 H26 FN3 O4)

Compound Name

2-(4-fluorophenoxy)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-(4-fluorophenoxy)-1-(3-{[3-(piperidine-1-carbonyl)pyridin-2-yl]oxy}pyrrolidin-1-yl)ethan-1-one

SMILES

O=C(COc(cc1)ccc1F)N(CC1)CC1Oc1ncccc1C(N1CCCCC1)=O

InChI

InChI=1S/C23H26FN3O4/c24-17-6-8-18(9-7-17)30-16-21(28)27-14-10-19(15-27)31-22-20(5-4-11-25-22)23(29)26-12-2-1-3-13-26/h4-9,11,19H,1-3,10,12-16H2/t19-/m1/s1

InChI Key

KNUYXYPGAWBADN-LJQANCHMSA-N

MDL Number (MFCD)

MFCD28994598

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.215

Distribution Coefficient, logD

2.215

Water Solubility, LogSw

-2.63

Polar Surface Area

56.873

Acid Dissociation Constant (pKa)

24.84

Base Dissociation Constant (pKb)

-0.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

P392-0497 in Drug Discovery

Included in Screening Libraries

Ligand-Gated Ion Channels Library (3887 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Ion Channels
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P392-0497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P392-0497?
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What is the minimum amount of P392-0497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P392-0497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P392-0497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P392-0497 available by request