P393-2057 Screening compound: 6-({1-[(4-chloro-2-methylphenyl)sulfonyl]-4-piperidyl}oxy)nicotinamide

P393-2057 Screening compound: 6-({1-[(4-chloro-2-methylphenyl)sulfonyl]-4-piperidyl}oxy)nicotinamide
P393-2057 Screening compound: 6-({1-[(4-chloro-2-methylphenyl)sulfonyl]-4-piperidyl}oxy)nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P393-2057
6-({1-[(4-chloro-2-methylphenyl)sulfonyl]-4-piperidyl}oxy)nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P393-2057

Molecular Formula

C18H20ClN3O4S (C18 H20 ClN3 O4 S)

Compound Name

6-({1-[(4-chloro-2-methylphenyl)sulfonyl]-4-piperidyl}oxy)nicotinamide

IUPAC name

n/a

SMILES

Cc(cc(cc1)Cl)c1S(N(CC1)CCC1Oc(cc1)ncc1C(N)=O)(=O)=O

InChI

InChI=1S/C18H20ClN3O4S/c1-12-10-14(19)3-4-16(12)27(24,25)22-8-6-15(7-9-22)26-17-5-2-13(11-21-17)18(20)23/h2-5,10-11,15H,6-9H2,1H3,(H2,20,23)

InChI Key

LWSSVXFQCZAOBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29003742

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.89

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.917

Distribution Coefficient, logD

2.917

Water Solubility, LogSw

-3.35

Polar Surface Area

81.308

Acid Dissociation Constant (pKa)

14.01

Base Dissociation Constant (pKb)

-0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

P393-2057 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P393-2057 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P393-2057?
Check Price and Availability of P393-2057, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P393-2057 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P393-2057
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P393-2057
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P393-2057 available by request