P492-0884 Screening compound: 2-[6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]-N-propylacetamide

P492-0884 Screening compound: 2-[6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]-N-propylacetamide
P492-0884 Screening compound: 2-[6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]-N-propylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P492-0884
2-[6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]-N-propylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P492-0884

Molecular Formula

C18H18N4O2S (C18 H18 N4 O2 S)

Compound Name

2-[6-oxo-5-(4-phenyl-1,3-thiazol-2-yl)-1,6-dihydropyrimidin-1-yl]-N-propylacetamide

IUPAC name

2-[6-oxo-5-(4-phenyl-13-thiazol-2-yl)-16-dihydropyrimidin-1-yl]-N-propylacetamide

SMILES

CCCNC(CN(C=NC=C1c2nc(-c3ccccc3)cs2)C1=O)=O

InChI

InChI=1S/C18H18N4O2S/c1-2-8-20-16(23)10-22-12-19-9-14(18(22)24)17-21-15(11-25-17)13-6-4-3-5-7-13/h3-7,9,11-12H,2,8,10H2,1H3,(H,20,23)

InChI Key

GMJFDDXNPOZNTE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27575959

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.134

Distribution Coefficient, logD

2.134

Water Solubility, LogSw

-2.67

Polar Surface Area

60.922

Acid Dissociation Constant (pKa)

15.97

Base Dissociation Constant (pKb)

3.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

P492-0884 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with P492-0884 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P492-0884?
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What is the minimum amount of P492-0884 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P492-0884
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P492-0884
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P492-0884 available by request