P492-0996 Screening compound: 3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one

P492-0996 Screening compound: 3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one
P492-0996 Screening compound: 3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P492-0996
3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P492-0996

Molecular Formula

C21H16N4O2S2 (C21 H16 N4 O2 S2)

Compound Name

3-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]-3,4-dihydropyrimidin-4-one

IUPAC name

3-[2-(23-dihydro-1H-indol-1-yl)-2-oxoethyl]-5-[4-(thiophen-2-yl)-13-thiazol-2-yl]-34-dihydropyrimidin-4-one

SMILES

O=C(CN(C=NC=C1c2nc(-c3cccs3)cs2)C1=O)N(CC1)c2c1cccc2

InChI

InChI=1S/C21H16N4O2S2/c26-19(25-8-7-14-4-1-2-5-17(14)25)11-24-13-22-10-15(21(24)27)20-23-16(12-29-20)18-6-3-9-28-18/h1-6,9-10,12-13H,7-8,11H2

InChI Key

YIKRDYZHSCBOOP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22596176

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.940

Distribution Coefficient, logD

2.940

Water Solubility, LogSw

-3.29

Polar Surface Area

52.779

Acid Dissociation Constant (pKa)

24.97

Base Dissociation Constant (pKb)

2.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

P492-0996 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P492-0996 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P492-0996?
Check Price and Availability of P492-0996, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P492-0996 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P492-0996
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P492-0996
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P492-0996 available by request