P637-0129 Screening compound: N-(6-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethoxy}pyridin-3-yl)cyclopropanecarboxamide

P637-0129 Screening compound: N-(6-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethoxy}pyridin-3-yl)cyclopropanecarboxamide
P637-0129 Screening compound: N-(6-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethoxy}pyridin-3-yl)cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P637-0129
N-(6-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethoxy}pyridin-3-yl)cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P637-0129

Molecular Formula

C20H23N5O3 (C20 H23 N5 O3)

Compound Name

N-(6-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethoxy}pyridin-3-yl)cyclopropanecarboxamide

IUPAC name

N-(6-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethoxy}pyridin-3-yl)cyclopropanecarboxamide

SMILES

O=C(COc(cc1)ncc1NC(C1CC1)=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C20H23N5O3/c26-19(25-11-9-24(10-12-25)17-3-1-2-8-21-17)14-28-18-7-6-16(13-22-18)23-20(27)15-4-5-15/h1-3,6-8,13,15H,4-5,9-12,14H2,(H,23,27)

InChI Key

ZMURXQKQOGBODI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27608605

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.013

Distribution Coefficient, logD

2.004

Water Solubility, LogSw

-2.24

Polar Surface Area

68.282

Acid Dissociation Constant (pKa)

11.98

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

P637-0129 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P637-0129 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P637-0129?
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What is the minimum amount of P637-0129 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P637-0129
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P637-0129
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P637-0129 available by request