P725-0020 Screening compound: 2-(1H-indol-3-yl)-1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone

P725-0020 Screening compound: 2-(1H-indol-3-yl)-1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone
P725-0020 Screening compound: 2-(1H-indol-3-yl)-1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound P725-0020
2-(1H-indol-3-yl)-1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P725-0020

Molecular Formula

C22H19N3OS (C22 H19 N3 OS)

Compound Name

2-(1H-indol-3-yl)-1-[5-(2-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-1-yl]-1-ethanone

IUPAC name

n/a

SMILES

Cc1nc(-c(cc2)cc(CC3)c2N3C(Cc2c[nH]c3c2cccc3)=O)cs1

InChI

InChI=1S/C22H19N3OS/c1-14-24-20(13-27-14)15-6-7-21-16(10-15)8-9-25(21)22(26)11-17-12-23-19-5-3-2-4-18(17)19/h2-7,10,12-13,23H,8-9,11H2,1H3

InChI Key

GLWYOJREESKQTR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11774638

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.48

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.833

Distribution Coefficient, logD

4.833

Water Solubility, LogSw

-4.70

Polar Surface Area

34.801

Acid Dissociation Constant (pKa)

16.51

Base Dissociation Constant (pKb)

1.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

P725-0020 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with P725-0020 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P725-0020?
Check Price and Availability of P725-0020, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P725-0020 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P725-0020
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P725-0020
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P725-0020 available by request