P734-2722 Screening compound: 2-(cyclopropylmethoxy)-1-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,6H,7H,8H,9H,10H-pyrido[1,2-a]azepin-4-one

P734-2722 Screening compound: 2-(cyclopropylmethoxy)-1-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,6H,7H,8H,9H,10H-pyrido[1,2-a]azepin-4-one
P734-2722 Screening compound: 2-(cyclopropylmethoxy)-1-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,6H,7H,8H,9H,10H-pyrido[1,2-a]azepin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P734-2722
2-(cyclopropylmethoxy)-1-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,6H,7H,8H,9H,10H-pyrido[1,2-a]azepin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P734-2722

Molecular Formula

C24H30N4O3 (C24 H30 N4 O3)

Compound Name

2-(cyclopropylmethoxy)-1-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H,6H,7H,8H,9H,10H-pyrido[1,2-a]azepin-4-one

IUPAC name

2-(cyclopropylmethoxy)-1-[4-(pyridin-2-yl)piperazine-1-carbonyl]-4H6H7H8H9H10H-pyrido[12-a]azepin-4-one

SMILES

O=C(C(C(OCC1CC1)=C1)=C(CCCCC2)N2C1=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C24H30N4O3/c29-22-16-20(31-17-18-8-9-18)23(19-6-2-1-5-11-28(19)22)24(30)27-14-12-26(13-15-27)21-7-3-4-10-25-21/h3-4,7,10,16,18H,1-2,5-6,8-9,11-15,17H2

InChI Key

JROAIITWMJDOHZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29002206

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.914

Distribution Coefficient, logD

2.905

Water Solubility, LogSw

-3.12

Polar Surface Area

53.192

Acid Dissociation Constant (pKa)

24.85

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.20

P734-2722 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

GPCR Targeted Library (31838 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Eye
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Targets:
  • Kinases
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P734-2722 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P734-2722?
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What is the minimum amount of P734-2722 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P734-2722
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P734-2722
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P734-2722 available by request