P804-0274 Screening compound: 2-{4-[3-(pyridin-3-yl)-1H-pyrazol-5-yl]piperazine-1-carbonyl}-1H-indole

P804-0274 Screening compound: 2-{4-[3-(pyridin-3-yl)-1H-pyrazol-5-yl]piperazine-1-carbonyl}-1H-indole
P804-0274 Screening compound: 2-{4-[3-(pyridin-3-yl)-1H-pyrazol-5-yl]piperazine-1-carbonyl}-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound P804-0274
2-{4-[3-(pyridin-3-yl)-1H-pyrazol-5-yl]piperazine-1-carbonyl}-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P804-0274

Molecular Formula

C21H20N6O (C21 H20 N6 O)

Compound Name

2-{4-[3-(pyridin-3-yl)-1H-pyrazol-5-yl]piperazine-1-carbonyl}-1H-indole

IUPAC name

2-{4-[3-(pyridin-3-yl)-1H-pyrazol-5-yl]piperazine-1-carbonyl}-1H-indole

SMILES

O=C(c1cc(cccc2)c2[nH]1)N(CC1)CCN1c1cc(-c2cnccc2)n[nH]1

InChI

InChI=1S/C21H20N6O/c28-21(19-12-15-4-1-2-6-17(15)23-19)27-10-8-26(9-11-27)20-13-18(24-25-20)16-5-3-7-22-14-16/h1-7,12-14,23H,8-11H2,(H,24,25)

InChI Key

USOILLHVLMWEEZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27615354

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.889

Distribution Coefficient, logD

2.881

Water Solubility, LogSw

-3.23

Polar Surface Area

60.967

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

P804-0274 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral HBV Library (10007 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Cyclic compounds
  • Mimetics
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P804-0274 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P804-0274?
Check Price and Availability of P804-0274, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P804-0274 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P804-0274
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P804-0274
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P804-0274 available by request