P843-0006 Screening compound: N-cyclopropyl-6-(3-{[(4-fluorophenyl)methyl]amino}pyrrolidin-1-yl)pyridine-3-carboxamide

P843-0006 Screening compound: N-cyclopropyl-6-(3-{[(4-fluorophenyl)methyl]amino}pyrrolidin-1-yl)pyridine-3-carboxamide
P843-0006 Screening compound: N-cyclopropyl-6-(3-{[(4-fluorophenyl)methyl]amino}pyrrolidin-1-yl)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P843-0006
N-cyclopropyl-6-(3-{[(4-fluorophenyl)methyl]amino}pyrrolidin-1-yl)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P843-0006

Molecular Formula

C20H23FN4O (C20 H23 FN4 O)

Compound Name

N-cyclopropyl-6-(3-{[(4-fluorophenyl)methyl]amino}pyrrolidin-1-yl)pyridine-3-carboxamide

IUPAC name

N-cyclopropyl-6-(3-{[(4-fluorophenyl)methyl]amino}pyrrolidin-1-yl)pyridine-3-carboxamide

SMILES

O=C(c(cc1)cnc1N(CC1)CC1NCc(cc1)ccc1F)NC1CC1

InChI

InChI=1S/C20H23FN4O/c21-16-4-1-14(2-5-16)11-22-18-9-10-25(13-18)19-8-3-15(12-23-19)20(26)24-17-6-7-17/h1-5,8,12,17-18,22H,6-7,9-11,13H2,(H,24,26)/t18-/m0/s1

InChI Key

KDRKLDWXVPZYRI-SFHVURJKSA-N

MDL Number (MFCD)

MFCD22597232

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.250

Distribution Coefficient, logD

1.693

Water Solubility, LogSw

-2.49

Polar Surface Area

48.151

Acid Dissociation Constant (pKa)

11.80

Base Dissociation Constant (pKb)

7.82

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

P843-0006 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P843-0006 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P843-0006?
Check Price and Availability of P843-0006, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P843-0006 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P843-0006
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P843-0006
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P843-0006 available by request