P867-0190 Screening compound: 4-bromo-2-({4-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperazin-1-yl}methyl)phenol

P867-0190 Screening compound: 4-bromo-2-({4-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperazin-1-yl}methyl)phenol
P867-0190 Screening compound: 4-bromo-2-({4-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperazin-1-yl}methyl)phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound P867-0190
4-bromo-2-({4-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperazin-1-yl}methyl)phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P867-0190

Molecular Formula

C19H20BrN5O (C19 H20 BrN5 O)

Compound Name

4-bromo-2-({4-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperazin-1-yl}methyl)phenol

IUPAC name

4-bromo-2-({4-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperazin-1-yl}methyl)phenol

SMILES

Oc(cc1)c(CN(CC2)CCN2c2cc(-c3ccncc3)n[nH]2)cc1Br

InChI

InChI=1S/C19H20BrN5O/c20-16-1-2-18(26)15(11-16)13-24-7-9-25(10-8-24)19-12-17(22-23-19)14-3-5-21-6-4-14/h1-6,11-12,26H,7-10,13H2,(H,22,23)

InChI Key

JPDUQYQEEZYYGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22597248

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.019

Distribution Coefficient, logD

2.872

Water Solubility, LogSw

-2.71

Polar Surface Area

55.161

Acid Dissociation Constant (pKa)

10.24

Base Dissociation Constant (pKb)

7.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

P867-0190 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P867-0190 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P867-0190?
Check Price and Availability of P867-0190, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P867-0190 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P867-0190
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P867-0190
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P867-0190 available by request