R344-0003 Screening compound: 4-tert-butyl-6-(trifluoromethyl)pyrimidin-2-amine

R344-0003 Screening compound: 4-tert-butyl-6-(trifluoromethyl)pyrimidin-2-amine
R344-0003 Screening compound: 4-tert-butyl-6-(trifluoromethyl)pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound R344-0003
4-tert-butyl-6-(trifluoromethyl)pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

R344-0003

Molecular Formula

C9H12F3N3 (C9 H12 F3 N3)

Compound Name

4-tert-butyl-6-(trifluoromethyl)pyrimidin-2-amine

IUPAC name

4-tert-butyl-6-(trifluoromethyl)pyrimidin-2-amine

SMILES

CC(C)(C)c1cc(C(F)(F)F)nc(N)n1

InChI

InChI=1S/C9H12F3N3/c1-8(2,3)5-4-6(9(10,11)12)15-7(13)14-5/h4H,1-3H3,(H2,13,14,15)

InChI Key

XIUFUZWOHSSRKX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00458223

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

219.21

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

2.823

Distribution Coefficient, logD

2.823

Water Solubility, LogSw

-2.85

Polar Surface Area

39.276

Acid Dissociation Constant (pKa)

17.30

Base Dissociation Constant (pKb)

3.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

R344-0003 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Akt-Targeted Library (14764 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Agro:
  • Agro
  • Agro
Structure:
  • Fragments
Targets:
  • Proteases
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with R344-0003 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound R344-0003?
Check Price and Availability of R344-0003, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of R344-0003 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for R344-0003
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for R344-0003
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of R344-0003 available by request