S214-1336F Screening compound: [(3R,4S)-3-(dimethylamino)-4-hydroxy-4-phenyltetrahydro-1(2H)-pyridinyl](phenyl)methanone

S214-1336F Screening compound: [(3R,4S)-3-(dimethylamino)-4-hydroxy-4-phenyltetrahydro-1(2H)-pyridinyl](phenyl)methanone
S214-1336F Screening compound: [(3R,4S)-3-(dimethylamino)-4-hydroxy-4-phenyltetrahydro-1(2H)-pyridinyl](phenyl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound S214-1336F
[(3R,4S)-3-(dimethylamino)-4-hydroxy-4-phenyltetrahydro-1(2H)-pyridinyl](phenyl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S214-1336F

Molecular Formula

C20H24N2O2 (C20 H24 N2 O2)

Compound Name

[(3R,4S)-3-(dimethylamino)-4-hydroxy-4-phenyltetrahydro-1(2H)-pyridinyl](phenyl)methanone

IUPAC name

(3R4S)-1-benzoyl-3-(dimethylamino)-4-phenylpiperidin-4-ol

SMILES

CN(C)[C@@H](CN(CC1)C(c2ccccc2)=O)[C@@]1(c1ccccc1)O

InChI

InChI=1S/C20H24N2O2/c1-21(2)18-15-22(19(23)16-9-5-3-6-10-16)14-13-20(18,24)17-11-7-4-8-12-17/h3-12,18,24H,13-15H2,1-2H3/t18-,20+/m0/s1

InChI Key

HGNSFWOYLDKLJP-AZUAARDMSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

324.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.002

Distribution Coefficient, logD

1.948

Water Solubility, LogSw

-2.00

Polar Surface Area

33.459

Acid Dissociation Constant (pKa)

14.99

Base Dissociation Constant (pKb)

6.52

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

35.00

S214-1336F in Drug Discovery

Included in Screening Libraries

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with S214-1336F chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S214-1336F?
Check Price and Availability of S214-1336F, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S214-1336F you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S214-1336F
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S214-1336F
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S214-1336F available by request