S214-1382 Screening compound: (3R,4S)-3-(dimethylamino)-1-[(4-methyl-1,3-thiazol-5-yl)methyl]-4-phenylhexahydro-4-pyridinol

S214-1382 Screening compound: (3R,4S)-3-(dimethylamino)-1-[(4-methyl-1,3-thiazol-5-yl)methyl]-4-phenylhexahydro-4-pyridinol
S214-1382 Screening compound: (3R,4S)-3-(dimethylamino)-1-[(4-methyl-1,3-thiazol-5-yl)methyl]-4-phenylhexahydro-4-pyridinol alternative view

Chemical Structure Depiction of ChemDiv screening compound S214-1382
(3R,4S)-3-(dimethylamino)-1-[(4-methyl-1,3-thiazol-5-yl)methyl]-4-phenylhexahydro-4-pyridinol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S214-1382

Molecular Formula

C18H25N3OS (C18 H25 N3 OS)

Compound Name

(3R,4S)-3-(dimethylamino)-1-[(4-methyl-1,3-thiazol-5-yl)methyl]-4-phenylhexahydro-4-pyridinol

IUPAC name

(3R4S)-3-(dimethylamino)-1-[(4-methyl-13-thiazol-5-yl)methyl]-4-phenylpiperidin-4-ol

SMILES

Cc1c(CN(CC[C@]2(c3ccccc3)O)C[C@@H]2N(C)C)scn1

InChI

InChI=1S/C18H25N3OS/c1-14-16(23-13-19-14)11-21-10-9-18(22,17(12-21)20(2)3)15-7-5-4-6-8-15/h4-8,13,17,22H,9-12H2,1-3H3/t17-,18+/m0/s1

InChI Key

RODVBAJNUCVWLL-ZWKOTPCHSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

331.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.040

Distribution Coefficient, logD

1.498

Water Solubility, LogSw

-1.63

Polar Surface Area

30.748

Acid Dissociation Constant (pKa)

14.99

Base Dissociation Constant (pKb)

7.79

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

50.00

S214-1382 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

DGK Inhibitors Library (10558 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with S214-1382 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S214-1382?
Check Price and Availability of S214-1382, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S214-1382 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S214-1382
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S214-1382
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S214-1382 available by request