S348-1783 Screening compound: 1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5,6-dimethyl-3-(4-methylphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

S348-1783 Screening compound: 1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5,6-dimethyl-3-(4-methylphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione
S348-1783 Screening compound: 1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5,6-dimethyl-3-(4-methylphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound S348-1783
1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5,6-dimethyl-3-(4-methylphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S348-1783

Molecular Formula

C25H24N4O3 (C25 H24 N4 O3)

Compound Name

1-[2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethyl]-5,6-dimethyl-3-(4-methylphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

IUPAC name

n/a

SMILES

Cc1cc(N(CC(N(CC2)c3c2cccc3)=O)C(N(c2ccc(C)cc2)C2=O)=O)c2n1C

InChI

InChI=1S/C25H24N4O3/c1-16-8-10-19(11-9-16)29-24(31)23-21(14-17(2)26(23)3)28(25(29)32)15-22(30)27-13-12-18-6-4-5-7-20(18)27/h4-11,14H,12-13,15H2,1-3H3

InChI Key

YUKKUUQWOGSTMG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29000100

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.751

Distribution Coefficient, logD

2.751

Water Solubility, LogSw

-3.08

Polar Surface Area

48.722

Acid Dissociation Constant (pKa)

22.20

Base Dissociation Constant (pKb)

0.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

S348-1783 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Indole Derivatives (10091 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Eye
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • Ion Channels
  • Others

References: we are preparing a list of scientific research reports with S348-1783 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S348-1783?
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What is the minimum amount of S348-1783 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S348-1783
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S348-1783
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S348-1783 available by request