S650-5297 Screening compound: 4-(dimethylamino)-N-[1-(3,4-dimethylphenyl)-2-oxopyrrolidin-3-yl]benzamide

S650-5297 Screening compound: 4-(dimethylamino)-N-[1-(3,4-dimethylphenyl)-2-oxopyrrolidin-3-yl]benzamide
S650-5297 Screening compound: 4-(dimethylamino)-N-[1-(3,4-dimethylphenyl)-2-oxopyrrolidin-3-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound S650-5297
4-(dimethylamino)-N-[1-(3,4-dimethylphenyl)-2-oxopyrrolidin-3-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

S650-5297

Molecular Formula

C21H25N3O2 (C21 H25 N3 O2)

Compound Name

4-(dimethylamino)-N-[1-(3,4-dimethylphenyl)-2-oxopyrrolidin-3-yl]benzamide

IUPAC name

4-(dimethylamino)-N-[1-(34-dimethylphenyl)-2-oxopyrrolidin-3-yl]benzamide

SMILES

Cc(cc1)c(C)cc1N(CCC1NC(c(cc2)ccc2N(C)C)=O)C1=O

InChI

InChI=1S/C21H25N3O2/c1-14-5-8-18(13-15(14)2)24-12-11-19(21(24)26)22-20(25)16-6-9-17(10-7-16)23(3)4/h5-10,13,19H,11-12H2,1-4H3,(H,22,25)/t19-/m0/s1

InChI Key

RPEJAYIHMHQINX-IBGZPJMESA-N

MDL Number (MFCD)

MFCD29018548

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.498

Distribution Coefficient, logD

3.497

Water Solubility, LogSw

-3.62

Polar Surface Area

43.918

Acid Dissociation Constant (pKa)

10.03

Base Dissociation Constant (pKb)

8.18

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.33

S650-5297 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with S650-5297 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound S650-5297?
Check Price and Availability of S650-5297, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of S650-5297 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for S650-5297
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for S650-5297
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of S650-5297 available by request