SA24-0014 Screening compound: {4,4-difluoro-1-[1-(3-methylthiophene-2-carbonyl)azetidin-3-yl]pyrrolidin-2-yl}methanol

SA24-0014 Screening compound: {4,4-difluoro-1-[1-(3-methylthiophene-2-carbonyl)azetidin-3-yl]pyrrolidin-2-yl}methanol
SA24-0014 Screening compound: {4,4-difluoro-1-[1-(3-methylthiophene-2-carbonyl)azetidin-3-yl]pyrrolidin-2-yl}methanol alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-0014
{4,4-difluoro-1-[1-(3-methylthiophene-2-carbonyl)azetidin-3-yl]pyrrolidin-2-yl}methanol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-0014

Molecular Formula

C14H18F2N2O2S (C14 H18 F2 N2 O2 S)

Compound Name

{4,4-difluoro-1-[1-(3-methylthiophene-2-carbonyl)azetidin-3-yl]pyrrolidin-2-yl}methanol

IUPAC name

[(2S)-44-difluoro-1-[1-(3-methylthiophene-2-carbonyl)azetidin-3-yl]pyrrolidin-2-yl]methanol

SMILES

Cc1c(C(N(C2)CC2N(C2)[C@H](CO)CC2(F)F)=O)scc1

InChI

InChI=1S/C14H18F2N2O2S/c1-9-2-3-21-12(9)13(20)17-5-11(6-17)18-8-14(15,16)4-10(18)7-19/h2-3,10-11,19H,4-8H2,1H3/t10-/m0/s1

InChI Key

UAFMPAIXAPJUCI-JTQLQIEISA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

316.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.639

Distribution Coefficient, logD

1.639

Water Solubility, LogSw

-2.11

Polar Surface Area

38.257

Acid Dissociation Constant (pKa)

15.36

Base Dissociation Constant (pKb)

4.56

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

64.29

SA24-0014 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

CNS Targets (44014 compounds)

NOTUM (Wnt signaling) Library (3881 compounds)

Ion Channels Focused Library (26372 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SA24-0014 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-0014?
Check Price and Availability of SA24-0014, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SA24-0014 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-0014
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-0014
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-0014 available by request