SA24-0237 Screening compound: 4-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}-5-(3-methylphenyl)-1,3-oxazole

SA24-0237 Screening compound: 4-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}-5-(3-methylphenyl)-1,3-oxazole
SA24-0237 Screening compound: 4-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}-5-(3-methylphenyl)-1,3-oxazole alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-0237
4-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}-5-(3-methylphenyl)-1,3-oxazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-0237

Molecular Formula

C21H25F2N3O3 (C21 H25 F2 N3 O3)

Compound Name

4-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}-5-(3-methylphenyl)-1,3-oxazole

IUPAC name

4-{3-[(2S)-2-(ethoxymethyl)-44-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}-5-(3-methylphenyl)-13-oxazole

SMILES

CCOC[C@H](CC(C1)(F)F)N1C(C1)CN1C(c1c(-c2cc(C)ccc2)ocn1)=O

InChI

InChI=1S/C21H25F2N3O3/c1-3-28-11-16-8-21(22,23)12-26(16)17-9-25(10-17)20(27)18-19(29-13-24-18)15-6-4-5-14(2)7-15/h4-7,13,16-17H,3,8-12H2,1-2H3/t16-/m1/s1

InChI Key

CUYWJUWVTOSIJL-MRXNPFEDSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.782

Distribution Coefficient, logD

2.782

Water Solubility, LogSw

-2.86

Polar Surface Area

47.019

Acid Dissociation Constant (pKa)

27.65

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.38

SA24-0237 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

NOTUM (Wnt signaling) Library (3881 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with SA24-0237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-0237?
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What is the minimum amount of SA24-0237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-0237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-0237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-0237 available by request