SA24-0271 Screening compound: 2-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}pyrimidine

SA24-0271 Screening compound: 2-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}pyrimidine
SA24-0271 Screening compound: 2-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-0271
2-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-0271

Molecular Formula

C15H20F2N4O2 (C15 H20 F2 N4 O2)

Compound Name

2-{3-[2-(ethoxymethyl)-4,4-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}pyrimidine

IUPAC name

2-{3-[(2S)-2-(ethoxymethyl)-44-difluoropyrrolidin-1-yl]azetidine-1-carbonyl}pyrimidine

SMILES

CCOC[C@H](CC(C1)(F)F)N1C(C1)CN1C(c1ncccn1)=O

InChI

InChI=1S/C15H20F2N4O2/c1-2-23-9-11-6-15(16,17)10-21(11)12-7-20(8-12)14(22)13-18-4-3-5-19-13/h3-5,11-12H,2,6-10H2,1H3/t11-/m1/s1

InChI Key

JWYSHDHJVIWGNW-LLVKDONJSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.029

Distribution Coefficient, logD

0.029

Water Solubility, LogSw

-0.71

Polar Surface Area

47.618

Acid Dissociation Constant (pKa)

27.72

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

66.67

SA24-0271 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA24-0271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-0271?
Check Price and Availability of SA24-0271, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SA24-0271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-0271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-0271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-0271 available by request