SA24-1665 Screening compound: 4-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}benzonitrile

SA24-1665 Screening compound: 4-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}benzonitrile
SA24-1665 Screening compound: 4-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-1665
4-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-1665

Molecular Formula

C17H19F2N3O2 (C17 H19 F2 N3 O2)

Compound Name

4-{3-[4,4-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}benzonitrile

IUPAC name

4-{3-[(2S)-44-difluoro-2-(methoxymethyl)pyrrolidin-1-yl]azetidine-1-carbonyl}benzonitrile

SMILES

COC[C@H](CC(C1)(F)F)N1C(C1)CN1C(c(cc1)ccc1C#N)=O

InChI

InChI=1S/C17H19F2N3O2/c1-24-10-14-6-17(18,19)11-22(14)15-8-21(9-15)16(23)13-4-2-12(7-20)3-5-13/h2-5,14-15H,6,8-11H2,1H3/t14-/m1/s1

InChI Key

ISWOSJKTDRITKD-CQSZACIVSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

335.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.368

Distribution Coefficient, logD

1.367

Water Solubility, LogSw

-1.91

Polar Surface Area

45.604

Acid Dissociation Constant (pKa)

27.42

Base Dissociation Constant (pKb)

4.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.94

SA24-1665 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • GPCR
  • Ion Channels
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with SA24-1665 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-1665?
Check Price and Availability of SA24-1665, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SA24-1665 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-1665
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-1665
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-1665 available by request