SA24-3911 Screening compound: (3-{(2S)-2-[(benzyloxy)methyl]-4,4-difluorotetrahydro-1H-pyrrol-1-yl}-1-azetanyl)(3-chloro-4-fluorophenyl)methanone

SA24-3911 Screening compound: (3-{(2S)-2-[(benzyloxy)methyl]-4,4-difluorotetrahydro-1H-pyrrol-1-yl}-1-azetanyl)(3-chloro-4-fluorophenyl)methanone
SA24-3911 Screening compound: (3-{(2S)-2-[(benzyloxy)methyl]-4,4-difluorotetrahydro-1H-pyrrol-1-yl}-1-azetanyl)(3-chloro-4-fluorophenyl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SA24-3911
(3-{(2S)-2-[(benzyloxy)methyl]-4,4-difluorotetrahydro-1H-pyrrol-1-yl}-1-azetanyl)(3-chloro-4-fluorophenyl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SA24-3911

Molecular Formula

C22H22ClF3N2O2 (C22 H22 ClF3 N2 O2)

Compound Name

(3-{(2S)-2-[(benzyloxy)methyl]-4,4-difluorotetrahydro-1H-pyrrol-1-yl}-1-azetanyl)(3-chloro-4-fluorophenyl)methanone

IUPAC name

(2S)-2-[(benzyloxy)methyl]-1-[1-(3-chloro-4-fluorobenzoyl)azetidin-3-yl]-44-difluoropyrrolidine

SMILES

O=C(c(cc1)cc(Cl)c1F)N(C1)CC1N(C1)[C@H](COCc2ccccc2)CC1(F)F

InChI

InChI=1S/C22H22ClF3N2O2/c23-19-8-16(6-7-20(19)24)21(29)27-10-18(11-27)28-14-22(25,26)9-17(28)13-30-12-15-4-2-1-3-5-15/h1-8,17-18H,9-14H2/t17-/m0/s1

InChI Key

PEPRADQOUBERKG-KRWDZBQOSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.749

Distribution Coefficient, logD

3.748

Water Solubility, LogSw

-4.34

Polar Surface Area

28.286

Acid Dissociation Constant (pKa)

27.42

Base Dissociation Constant (pKb)

4.46

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.91

SA24-3911 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SA24-3911 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SA24-3911?
Check Price and Availability of SA24-3911, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SA24-3911 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SA24-3911
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SA24-3911
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SA24-3911 available by request