SB01-0035 Screening compound: 2-{[5-(4-chloro-2-methoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}-6-methylpyridine

SB01-0035 Screening compound: 2-{[5-(4-chloro-2-methoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}-6-methylpyridine
SB01-0035 Screening compound: 2-{[5-(4-chloro-2-methoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}-6-methylpyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound SB01-0035
2-{[5-(4-chloro-2-methoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}-6-methylpyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB01-0035

Molecular Formula

C22H23ClN4O3 (C22 H23 ClN4 O3)

Compound Name

2-{[5-(4-chloro-2-methoxybenzoyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-3-yl]methoxy}-6-methylpyridine

IUPAC name

2-{[5-(4-chloro-2-methoxybenzoyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]methoxy}-6-methylpyridine

SMILES

Cc1cccc(OCc2nn(C)c(CC3)c2CN3C(c(ccc(Cl)c2)c2OC)=O)n1

InChI

InChI=1S/C22H23ClN4O3/c1-14-5-4-6-21(24-14)30-13-18-17-12-27(10-9-19(17)26(2)25-18)22(28)16-8-7-15(23)11-20(16)29-3/h4-8,11H,9-10,12-13H2,1-3H3

InChI Key

HZDDHDDXXXVWBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32244403

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.9

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.278

Distribution Coefficient, logD

3.277

Water Solubility, LogSw

-3.61

Polar Surface Area

55.242

Acid Dissociation Constant (pKa)

21.95

Base Dissociation Constant (pKb)

3.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.82

SB01-0035 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SB01-0035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB01-0035?
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What is the minimum amount of SB01-0035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB01-0035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB01-0035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB01-0035 available by request