SB35-1143 Screening compound: 5-[(2S)-1-cyclopentyl-4,4-difluorotetrahydro-1H-pyrrol-2-yl]-3-methyl-1H-1,2,4-triazole

SB35-1143 Screening compound: 5-[(2S)-1-cyclopentyl-4,4-difluorotetrahydro-1H-pyrrol-2-yl]-3-methyl-1H-1,2,4-triazole
SB35-1143 Screening compound: 5-[(2S)-1-cyclopentyl-4,4-difluorotetrahydro-1H-pyrrol-2-yl]-3-methyl-1H-1,2,4-triazole alternative view

Chemical Structure Depiction of ChemDiv screening compound SB35-1143
5-[(2S)-1-cyclopentyl-4,4-difluorotetrahydro-1H-pyrrol-2-yl]-3-methyl-1H-1,2,4-triazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB35-1143

Molecular Formula

C12H18F2N4 (C12 H18 F2 N4)

Compound Name

5-[(2S)-1-cyclopentyl-4,4-difluorotetrahydro-1H-pyrrol-2-yl]-3-methyl-1H-1,2,4-triazole

IUPAC name

5-[(2S)-1-cyclopentyl-44-difluoropyrrolidin-2-yl]-3-methyl-1H-124-triazole

SMILES

Cc1n[nH]c([C@H](CC(C2)(F)F)N2C2CCCC2)n1

InChI

InChI=1S/C12H18F2N4/c1-8-15-11(17-16-8)10-6-12(13,14)7-18(10)9-4-2-3-5-9/h9-10H,2-7H2,1H3,(H,15,16,17)/t10-/m1/s1

InChI Key

UVIBEMKTPIOXPF-SNVBAGLBSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

256.3

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.147

Distribution Coefficient, logD

2.144

Water Solubility, LogSw

-2.24

Polar Surface Area

37.281

Acid Dissociation Constant (pKa)

10.21

Base Dissociation Constant (pKb)

4.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

83.33

SB35-1143 in Drug Discovery

Included in Screening Libraries

3D-Fragment Library (4274 compounds)

CNS BBB Library (22607 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with SB35-1143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB35-1143?
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What is the minimum amount of SB35-1143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB35-1143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB35-1143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB35-1143 available by request