SB74-0142 Screening compound: (3S,5R)-3-[(4-benzylpiperidino)carbonyl]-7-isopropyl-2,7-diazaspiro[4.4]nonan-1-one

SB74-0142 Screening compound: (3S,5R)-3-[(4-benzylpiperidino)carbonyl]-7-isopropyl-2,7-diazaspiro[4.4]nonan-1-one
SB74-0142 Screening compound: (3S,5R)-3-[(4-benzylpiperidino)carbonyl]-7-isopropyl-2,7-diazaspiro[4.4]nonan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound SB74-0142
(3S,5R)-3-[(4-benzylpiperidino)carbonyl]-7-isopropyl-2,7-diazaspiro[4.4]nonan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB74-0142

Molecular Formula

C23H33N3O2 (C23 H33 N3 O2)

Compound Name

(3S,5R)-3-[(4-benzylpiperidino)carbonyl]-7-isopropyl-2,7-diazaspiro[4.4]nonan-1-one

IUPAC name

(3S5R)-3-(4-benzylpiperidine-1-carbonyl)-7-(propan-2-yl)-27-diazaspiro[4.4]nonan-1-one

SMILES

CC(C)N(CC1)C[C@@]1(C[C@@H](C(N1CCC(Cc2ccccc2)CC1)=O)N1)C1=O

InChI

InChI=1S/C23H33N3O2/c1-17(2)26-13-10-23(16-26)15-20(24-22(23)28)21(27)25-11-8-19(9-12-25)14-18-6-4-3-5-7-18/h3-7,17,19-20H,8-16H2,1-2H3,(H,24,28)/t20-,23-/m1/s1

InChI Key

MINIWNZIKKXOOI-NFBKMPQASA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.849

Distribution Coefficient, logD

-1.320

Water Solubility, LogSw

-3.39

Polar Surface Area

46.768

Acid Dissociation Constant (pKa)

9.63

Base Dissociation Constant (pKb)

10.15

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

65.22

SB74-0142 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Natural-Product-Based Library (3730 compounds)

Ion Channels Focused Library (26372 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Structure:
  • Pool
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SB74-0142 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB74-0142?
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What is the minimum amount of SB74-0142 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB74-0142
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB74-0142
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB74-0142 available by request