SB99-0519 Screening compound: 3-{5-[(6-methoxy-3-pyridyl)carbonyl]-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}-1-(1-pyrrolidinyl)-1-propanone

SB99-0519 Screening compound: 3-{5-[(6-methoxy-3-pyridyl)carbonyl]-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}-1-(1-pyrrolidinyl)-1-propanone
SB99-0519 Screening compound: 3-{5-[(6-methoxy-3-pyridyl)carbonyl]-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}-1-(1-pyrrolidinyl)-1-propanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SB99-0519
3-{5-[(6-methoxy-3-pyridyl)carbonyl]-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}-1-(1-pyrrolidinyl)-1-propanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SB99-0519

Molecular Formula

C21H27N5O3 (C21 H27 N5 O3)

Compound Name

3-{5-[(6-methoxy-3-pyridyl)carbonyl]-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}-1-(1-pyrrolidinyl)-1-propanone

IUPAC name

3-[5-(6-methoxypyridine-3-carbonyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-3-yl]-1-(pyrrolidin-1-yl)propan-1-one

SMILES

Cn1nc(CCC(N2CCCC2)=O)c(C2)c1CCN2C(c(cc1)cnc1OC)=O

InChI

InChI=1S/C21H27N5O3/c1-24-18-9-12-26(21(28)15-5-7-19(29-2)22-13-15)14-16(18)17(23-24)6-8-20(27)25-10-3-4-11-25/h5,7,13H,3-4,6,8-12,14H2,1-2H3

InChI Key

GAMKGJRVBYBTDV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32252269

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.681

Distribution Coefficient, logD

0.681

Water Solubility, LogSw

-1.44

Polar Surface Area

65.130

Acid Dissociation Constant (pKa)

21.75

Base Dissociation Constant (pKb)

1.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.38

SB99-0519 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with SB99-0519 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SB99-0519?
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What is the minimum amount of SB99-0519 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SB99-0519
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SB99-0519
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SB99-0519 available by request