SC05-0136 Screening compound: N'-(2,5-difluorophenyl)-N-[2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]-N-(1-methyl-4-piperidyl)urea

SC05-0136 Screening compound: N'-(2,5-difluorophenyl)-N-[2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]-N-(1-methyl-4-piperidyl)urea
SC05-0136 Screening compound: N'-(2,5-difluorophenyl)-N-[2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]-N-(1-methyl-4-piperidyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound SC05-0136
N'-(2,5-difluorophenyl)-N-[2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]-N-(1-methyl-4-piperidyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC05-0136

Molecular Formula

C18H23F2N5O2 (C18 H23 F2 N5 O2)

Compound Name

N'-(2,5-difluorophenyl)-N-[2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]-N-(1-methyl-4-piperidyl)urea

IUPAC name

3-(25-difluorophenyl)-1-[2-(5-methyl-124-oxadiazol-3-yl)ethyl]-1-(1-methylpiperidin-4-yl)urea

SMILES

Cc1nc(CCN(C2CCN(C)CC2)C(Nc(cc(cc2)F)c2F)=O)no1

InChI

InChI=1S/C18H23F2N5O2/c1-12-21-17(23-27-12)7-10-25(14-5-8-24(2)9-6-14)18(26)22-16-11-13(19)3-4-15(16)20/h3-4,11,14H,5-10H2,1-2H3,(H,22,26)

InChI Key

YKKTVKYEVVNRBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32253205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.749

Distribution Coefficient, logD

0.919

Water Solubility, LogSw

-3.15

Polar Surface Area

59.168

Acid Dissociation Constant (pKa)

10.62

Base Dissociation Constant (pKb)

9.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

SC05-0136 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with SC05-0136 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC05-0136?
Check Price and Availability of SC05-0136, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC05-0136 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC05-0136
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC05-0136
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC05-0136 available by request