SC12-1052 Screening compound: 5-cyclopropyl-N-[3-(4-methylpiperazino)propyl]-N-tetrahydro-2H-pyran-4-yl-1H-pyrazole-3-carboxamide

SC12-1052 Screening compound: 5-cyclopropyl-N-[3-(4-methylpiperazino)propyl]-N-tetrahydro-2H-pyran-4-yl-1H-pyrazole-3-carboxamide
SC12-1052 Screening compound: 5-cyclopropyl-N-[3-(4-methylpiperazino)propyl]-N-tetrahydro-2H-pyran-4-yl-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SC12-1052
5-cyclopropyl-N-[3-(4-methylpiperazino)propyl]-N-tetrahydro-2H-pyran-4-yl-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC12-1052

Molecular Formula

C20H33N5O2 (C20 H33 N5 O2)

Compound Name

5-cyclopropyl-N-[3-(4-methylpiperazino)propyl]-N-tetrahydro-2H-pyran-4-yl-1H-pyrazole-3-carboxamide

IUPAC name

5-cyclopropyl-N-[3-(4-methylpiperazin-1-yl)propyl]-N-(oxan-4-yl)-1H-pyrazole-3-carboxamide

SMILES

CN1CCN(CCCN(C2CCOCC2)C(c2n[nH]c(C3CC3)c2)=O)CC1

InChI

InChI=1S/C20H33N5O2/c1-23-9-11-24(12-10-23)7-2-8-25(17-5-13-27-14-6-17)20(26)19-15-18(21-22-19)16-3-4-16/h15-17H,2-14H2,1H3,(H,21,22)

InChI Key

PGXRZAGARHIHSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32254602

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.318

Distribution Coefficient, logD

0.393

Water Solubility, LogSw

-1.82

Polar Surface Area

53.782

Acid Dissociation Constant (pKa)

12.76

Base Dissociation Constant (pKb)

8.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

80.00

SC12-1052 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS BBB Library (22607 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with SC12-1052 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC12-1052?
Check Price and Availability of SC12-1052, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC12-1052 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC12-1052
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC12-1052
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC12-1052 available by request