SC15-0266 Screening compound: 1-{[1-(3-chlorobenzyl)-4-piperidyl]methyl}-4-[(2-pyrimidinyloxy)methyl]-2-pyrrolidinone

SC15-0266 Screening compound: 1-{[1-(3-chlorobenzyl)-4-piperidyl]methyl}-4-[(2-pyrimidinyloxy)methyl]-2-pyrrolidinone
SC15-0266 Screening compound: 1-{[1-(3-chlorobenzyl)-4-piperidyl]methyl}-4-[(2-pyrimidinyloxy)methyl]-2-pyrrolidinone alternative view

Chemical Structure Depiction of ChemDiv screening compound SC15-0266
1-{[1-(3-chlorobenzyl)-4-piperidyl]methyl}-4-[(2-pyrimidinyloxy)methyl]-2-pyrrolidinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC15-0266

Molecular Formula

C22H27ClN4O2 (C22 H27 ClN4 O2)

Compound Name

1-{[1-(3-chlorobenzyl)-4-piperidyl]methyl}-4-[(2-pyrimidinyloxy)methyl]-2-pyrrolidinone

IUPAC name

1-({1-[(3-chlorophenyl)methyl]piperidin-4-yl}methyl)-4-[(pyrimidin-2-yloxy)methyl]pyrrolidin-2-one

SMILES

O=C1N(CC2CCN(Cc3cccc(Cl)c3)CC2)CC(COc2ncccn2)C1

InChI

InChI=1S/C22H27ClN4O2/c23-20-4-1-3-18(11-20)13-26-9-5-17(6-10-26)14-27-15-19(12-21(27)28)16-29-22-24-7-2-8-25-22/h1-4,7-8,11,17,19H,5-6,9-10,12-16H2/t19-/m1/s1

InChI Key

AHXSJOMOSMZUFJ-LJQANCHMSA-N

MDL Number (MFCD)

MFCD32255749

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.953

Distribution Coefficient, logD

1.374

Water Solubility, LogSw

-3.21

Polar Surface Area

47.631

Acid Dissociation Constant (pKa)

17.24

Base Dissociation Constant (pKb)

8.97

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

SC15-0266 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with SC15-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC15-0266?
Check Price and Availability of SC15-0266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC15-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC15-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC15-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC15-0266 available by request