SC21-0007 Screening compound: {3-[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]-1-ethyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}(3-fluoro-4-pyridyl)methanone

SC21-0007 Screening compound: {3-[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]-1-ethyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}(3-fluoro-4-pyridyl)methanone
SC21-0007 Screening compound: {3-[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]-1-ethyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}(3-fluoro-4-pyridyl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SC21-0007
{3-[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]-1-ethyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}(3-fluoro-4-pyridyl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC21-0007

Molecular Formula

C22H25FN6O (C22 H25 FN6 O)

Compound Name

{3-[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]-1-ethyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}(3-fluoro-4-pyridyl)methanone

IUPAC name

4-{3-[1-(cyclopropylmethyl)-5-methyl-1H-imidazol-2-yl]-1-ethyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-5-carbonyl}-3-fluoropyridine

SMILES

CCn(c(CC1)c2CN1C(c(ccnc1)c1F)=O)nc2-c1ncc(C)n1CC1CC1

InChI

InChI=1S/C22H25FN6O/c1-3-29-19-7-9-27(22(30)16-6-8-24-11-18(16)23)13-17(19)20(26-29)21-25-10-14(2)28(21)12-15-4-5-15/h6,8,10-11,15H,3-5,7,9,12-13H2,1-2H3

InChI Key

LHLMNLGXZHMANN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32257374

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.977

Distribution Coefficient, logD

1.974

Water Solubility, LogSw

-2.10

Polar Surface Area

51.959

Acid Dissociation Constant (pKa)

21.53

Base Dissociation Constant (pKb)

5.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.46

SC21-0007 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with SC21-0007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC21-0007?
Check Price and Availability of SC21-0007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC21-0007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC21-0007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC21-0007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC21-0007 available by request