SC72-0387 Screening compound: 1-(2'-cyclopropyl-1H,7'H-spiro[azetidine-3,5'-furo[3,4-d]pyrimidin]-1-yl)-2,2-difluoroethanone

SC72-0387 Screening compound: 1-(2'-cyclopropyl-1H,7'H-spiro[azetidine-3,5'-furo[3,4-d]pyrimidin]-1-yl)-2,2-difluoroethanone
SC72-0387 Screening compound: 1-(2'-cyclopropyl-1H,7'H-spiro[azetidine-3,5'-furo[3,4-d]pyrimidin]-1-yl)-2,2-difluoroethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound SC72-0387
1-(2'-cyclopropyl-1H,7'H-spiro[azetidine-3,5'-furo[3,4-d]pyrimidin]-1-yl)-2,2-difluoroethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC72-0387

Molecular Formula

C13H13F2N3O2 (C13 H13 F2 N3 O2)

Compound Name

1-(2'-cyclopropyl-1H,7'H-spiro[azetidine-3,5'-furo[3,4-d]pyrimidin]-1-yl)-2,2-difluoroethanone

IUPAC name

1-{2'-cyclopropyl-7'H-spiro[azetidine-35'-furo[34-d]pyrimidin]-1-yl}-22-difluoroethan-1-one

SMILES

O=C(C(F)F)N(C1)CC11OCc2c1cnc(C1CC1)n2

InChI

InChI=1S/C13H13F2N3O2/c14-10(15)12(19)18-5-13(6-18)8-3-16-11(7-1-2-7)17-9(8)4-20-13/h3,7,10H,1-2,4-6H2

InChI Key

VMALEPLOTBHUMU-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

281.26

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

0.668

Distribution Coefficient, logD

0.667

Water Solubility, LogSw

-1.67

Polar Surface Area

46.012

Acid Dissociation Constant (pKa)

18.46

Base Dissociation Constant (pKb)

4.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.54

SC72-0387 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with SC72-0387 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC72-0387?
Check Price and Availability of SC72-0387, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SC72-0387 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC72-0387
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC72-0387
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC72-0387 available by request