SC74-0485 Screening compound: N~3~-[(1S,2R,4R)-4-[(isopropylamino)carbonyl]-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]nicotinamide

SC74-0485 Screening compound: N~3~-[(1S,2R,4R)-4-[(isopropylamino)carbonyl]-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]nicotinamide
SC74-0485 Screening compound: N~3~-[(1S,2R,4R)-4-[(isopropylamino)carbonyl]-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SC74-0485
N~3~-[(1S,2R,4R)-4-[(isopropylamino)carbonyl]-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC74-0485

Molecular Formula

C23H25N5O3 (C23 H25 N5 O3)

Compound Name

N~3~-[(1S,2R,4R)-4-[(isopropylamino)carbonyl]-2-(3-phenyl-1,2,4-oxadiazol-5-yl)cyclopentyl]nicotinamide

IUPAC name

N-[(1S2R4R)-2-(3-phenyl-124-oxadiazol-5-yl)-4-[(propan-2-yl)carbamoyl]cyclopentyl]pyridine-3-carboxamide

SMILES

CC(C)NC([C@H](C[C@H]1c2nc(-c3ccccc3)no2)C[C@@H]1NC(c1cnccc1)=O)=O

InChI

InChI=1S/C23H25N5O3/c1-14(2)25-22(30)17-11-18(19(12-17)26-21(29)16-9-6-10-24-13-16)23-27-20(28-31-23)15-7-4-3-5-8-15/h3-10,13-14,17-19H,11-12H2,1-2H3,(H,25,30)(H,26,29)/t17-,18+,19-/m0/s1

InChI Key

HQMHRMIDMWGISK-OTWHNJEPSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.825

Distribution Coefficient, logD

2.825

Water Solubility, LogSw

-3.01

Polar Surface Area

89.716

Acid Dissociation Constant (pKa)

14.08

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

34.78

SC74-0485 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with SC74-0485 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC74-0485?
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What is the minimum amount of SC74-0485 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC74-0485
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC74-0485
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC74-0485 available by request