SC74-0733 Screening compound: 1,5-dimethyl-N~3~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-1H-pyrazole-3-carboxamide

SC74-0733 Screening compound: 1,5-dimethyl-N~3~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-1H-pyrazole-3-carboxamide
SC74-0733 Screening compound: 1,5-dimethyl-N~3~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SC74-0733
1,5-dimethyl-N~3~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SC74-0733

Molecular Formula

C24H28N6O3 (C24 H28 N6 O3)

Compound Name

1,5-dimethyl-N~3~-[(1S,2R,4R)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)-4-(1-pyrrolidinylcarbonyl)cyclopentyl]-1H-pyrazole-3-carboxamide

IUPAC name

15-dimethyl-N-[(1S2R4R)-2-(3-phenyl-124-oxadiazol-5-yl)-4-(pyrrolidine-1-carbonyl)cyclopentyl]-1H-pyrazole-3-carboxamide

SMILES

Cc1cc(C(N[C@@H](C[C@@H](C2)C(N3CCCC3)=O)[C@@H]2c2nc(-c3ccccc3)no2)=O)nn1C

InChI

InChI=1S/C24H28N6O3/c1-15-12-20(27-29(15)2)22(31)25-19-14-17(24(32)30-10-6-7-11-30)13-18(19)23-26-21(28-33-23)16-8-4-3-5-9-16/h3-5,8-9,12,17-19H,6-7,10-11,13-14H2,1-2H3,(H,25,31)/t17-,18+,19-/m0/s1

InChI Key

OTNYSEDTTIOKON-OTWHNJEPSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.976

Distribution Coefficient, logD

2.976

Water Solubility, LogSw

-3.34

Polar Surface Area

88.040

Acid Dissociation Constant (pKa)

15.51

Base Dissociation Constant (pKb)

-0.51

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

45.83

SC74-0733 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with SC74-0733 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SC74-0733?
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What is the minimum amount of SC74-0733 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SC74-0733
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SC74-0733
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SC74-0733 available by request