SD25-0301 Screening compound: N~1~-cyclopropyl-3-(2-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}-2-azaspiro[4.5]dec-4-yl)propanamide

SD25-0301 Screening compound: N~1~-cyclopropyl-3-(2-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}-2-azaspiro[4.5]dec-4-yl)propanamide
SD25-0301 Screening compound: N~1~-cyclopropyl-3-(2-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}-2-azaspiro[4.5]dec-4-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound SD25-0301
N~1~-cyclopropyl-3-(2-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}-2-azaspiro[4.5]dec-4-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

SD25-0301

Molecular Formula

C25H31FN4O2 (C25 H31 FN4 O2)

Compound Name

N~1~-cyclopropyl-3-(2-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}-2-azaspiro[4.5]dec-4-yl)propanamide

IUPAC name

N-cyclopropyl-3-{2-[3-(4-fluorophenyl)-1H-pyrazole-4-carbonyl]-2-azaspiro[4.5]decan-4-yl}propanamide

SMILES

O=C(CCC(CN(C1)C(c2c[nH]nc2-c(cc2)ccc2F)=O)C11CCCCC1)NC1CC1

InChI

InChI=1S/C25H31FN4O2/c26-19-7-4-17(5-8-19)23-21(14-27-29-23)24(32)30-15-18(6-11-22(31)28-20-9-10-20)25(16-30)12-2-1-3-13-25/h4-5,7-8,14,18,20H,1-3,6,9-13,15-16H2,(H,27,29)(H,28,31)/t18-/m1/s1

InChI Key

GMBAKLBOUICXLX-GOSISDBHSA-N

MDL Number (MFCD)

MFCD32259611

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.288

Distribution Coefficient, logD

3.288

Water Solubility, LogSw

-3.59

Polar Surface Area

65.486

Acid Dissociation Constant (pKa)

11.78

Base Dissociation Constant (pKb)

-0.11

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

56.00

SD25-0301 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

CORONAVIRUS Library (20774 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with SD25-0301 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound SD25-0301?
Check Price and Availability of SD25-0301, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of SD25-0301 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for SD25-0301
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for SD25-0301
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of SD25-0301 available by request