T001-1490 Screening compound: 2-(4-acryloylpiperazino)-N~1~-(4-fluorophenyl)acetamide

T001-1490 Screening compound: 2-(4-acryloylpiperazino)-N~1~-(4-fluorophenyl)acetamide
T001-1490 Screening compound: 2-(4-acryloylpiperazino)-N~1~-(4-fluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T001-1490
2-(4-acryloylpiperazino)-N~1~-(4-fluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T001-1490

Molecular Formula

C15H18FN3O2 (C15 H18 FN3 O2)

Compound Name

2-(4-acryloylpiperazino)-N~1~-(4-fluorophenyl)acetamide

IUPAC name

N-(4-fluorophenyl)-2-[4-(prop-2-enoyl)piperazin-1-yl]acetamide

SMILES

C=CC(N1CCN(CC(Nc(cc2)ccc2F)=O)CC1)=O

InChI

InChI=1S/C15H18FN3O2/c1-2-15(21)19-9-7-18(8-10-19)11-14(20)17-13-5-3-12(16)4-6-13/h2-6H,1,7-11H2,(H,17,20)

InChI Key

NLKMBDPZOLGYPE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32260263

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

291.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.604

Distribution Coefficient, logD

1.603

Water Solubility, LogSw

-2.27

Polar Surface Area

43.321

Acid Dissociation Constant (pKa)

10.78

Base Dissociation Constant (pKb)

3.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

T001-1490 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Covalent Fragments Smart Library (839 compounds)

KRAS-Targeted Library (16000 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T001-1490 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T001-1490?
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What is the minimum amount of T001-1490 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T001-1490
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T001-1490
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T001-1490 available by request