T143-0461 Screening compound: 1-(4-ethoxyphenyl)-3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]urea

T143-0461 Screening compound: 1-(4-ethoxyphenyl)-3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]urea
T143-0461 Screening compound: 1-(4-ethoxyphenyl)-3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound T143-0461
1-(4-ethoxyphenyl)-3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T143-0461

Molecular Formula

C24H28FN5O2 (C24 H28 FN5 O2)

Compound Name

1-(4-ethoxyphenyl)-3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]urea

IUPAC name

1-(4-ethoxyphenyl)-3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]urea

SMILES

CCOc(cc1)ccc1NC(Nc(n(C)nc1-c2cccc(F)c2)c1N1CCCCC1)=O

InChI

InChI=1S/C24H28FN5O2/c1-3-32-20-12-10-19(11-13-20)26-24(31)27-23-22(30-14-5-4-6-15-30)21(28-29(23)2)17-8-7-9-18(25)16-17/h7-13,16H,3-6,14-15H2,1-2H3,(H2,26,27,31)

InChI Key

QQDOKGKDJZCAAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31994421

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.040

Distribution Coefficient, logD

5.040

Water Solubility, LogSw

-4.54

Polar Surface Area

56.949

Acid Dissociation Constant (pKa)

11.28

Base Dissociation Constant (pKb)

5.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

T143-0461 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with T143-0461 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T143-0461?
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What is the minimum amount of T143-0461 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T143-0461
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T143-0461
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T143-0461 available by request