T143-0498 Screening compound: 3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]-1-(4-methoxy-2-methylphenyl)urea

T143-0498 Screening compound: 3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]-1-(4-methoxy-2-methylphenyl)urea
T143-0498 Screening compound: 3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]-1-(4-methoxy-2-methylphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound T143-0498
3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]-1-(4-methoxy-2-methylphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T143-0498

Molecular Formula

C24H28FN5O2 (C24 H28 FN5 O2)

Compound Name

3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]-1-(4-methoxy-2-methylphenyl)urea

IUPAC name

3-[3-(3-fluorophenyl)-1-methyl-4-(piperidin-1-yl)-1H-pyrazol-5-yl]-1-(4-methoxy-2-methylphenyl)urea

SMILES

Cc(cc(cc1)OC)c1NC(Nc(n(C)nc1-c2cccc(F)c2)c1N1CCCCC1)=O

InChI

InChI=1S/C24H28FN5O2/c1-16-14-19(32-3)10-11-20(16)26-24(31)27-23-22(30-12-5-4-6-13-30)21(28-29(23)2)17-8-7-9-18(25)15-17/h7-11,14-15H,4-6,12-13H2,1-3H3,(H2,26,27,31)

InChI Key

KVBGMZJJWZVTGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31973283

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.702

Distribution Coefficient, logD

4.701

Water Solubility, LogSw

-4.43

Polar Surface Area

56.671

Acid Dissociation Constant (pKa)

10.74

Base Dissociation Constant (pKb)

5.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

T143-0498 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with T143-0498 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T143-0498?
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What is the minimum amount of T143-0498 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T143-0498
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T143-0498
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T143-0498 available by request