T160-0045 Screening compound: 4-{[1-(2-methoxyethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(thiophene-3-carbonyl)piperidine

T160-0045 Screening compound: 4-{[1-(2-methoxyethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(thiophene-3-carbonyl)piperidine
T160-0045 Screening compound: 4-{[1-(2-methoxyethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(thiophene-3-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound T160-0045
4-{[1-(2-methoxyethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(thiophene-3-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T160-0045

Molecular Formula

C18H25N3O2S (C18 H25 N3 O2 S)

Compound Name

4-{[1-(2-methoxyethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(thiophene-3-carbonyl)piperidine

IUPAC name

4-{[1-(2-methoxyethyl)-5-methyl-1H-imidazol-2-yl]methyl}-1-(thiophene-3-carbonyl)piperidine

SMILES

Cc1cnc(CC(CC2)CCN2C(c2cscc2)=O)n1CCOC

InChI

InChI=1S/C18H25N3O2S/c1-14-12-19-17(21(14)8-9-23-2)11-15-3-6-20(7-4-15)18(22)16-5-10-24-13-16/h5,10,12-13,15H,3-4,6-9,11H2,1-2H3

InChI Key

MPGMPIGZQFNURX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31979963

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

347.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.297

Distribution Coefficient, logD

0.364

Water Solubility, LogSw

-2.34

Polar Surface Area

38.387

Acid Dissociation Constant (pKa)

24.76

Base Dissociation Constant (pKb)

9.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.56

T160-0045 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T160-0045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T160-0045?
Check Price and Availability of T160-0045, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T160-0045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T160-0045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T160-0045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T160-0045 available by request