T160-0424 Screening compound: 4-{[1-(3-methoxypropyl)-5-methyl-1H-imidazol-2-yl]methyl}-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide

T160-0424 Screening compound: 4-{[1-(3-methoxypropyl)-5-methyl-1H-imidazol-2-yl]methyl}-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide
T160-0424 Screening compound: 4-{[1-(3-methoxypropyl)-5-methyl-1H-imidazol-2-yl]methyl}-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T160-0424
4-{[1-(3-methoxypropyl)-5-methyl-1H-imidazol-2-yl]methyl}-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T160-0424

Molecular Formula

C23H34N4O2 (C23 H34 N4 O2)

Compound Name

4-{[1-(3-methoxypropyl)-5-methyl-1H-imidazol-2-yl]methyl}-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide

IUPAC name

4-{[1-(3-methoxypropyl)-5-methyl-1H-imidazol-2-yl]methyl}-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide

SMILES

Cc1cnc(CC(CC2)CCN2C(NCc2ccc(C)cc2)=O)n1CCCOC

InChI

InChI=1S/C23H34N4O2/c1-18-5-7-21(8-6-18)17-25-23(28)26-12-9-20(10-13-26)15-22-24-16-19(2)27(22)11-4-14-29-3/h5-8,16,20H,4,9-15,17H2,1-3H3,(H,25,28)

InChI Key

OJUBCPJUYNKUTM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31999552

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.126

Distribution Coefficient, logD

0.750

Water Solubility, LogSw

-2.95

Polar Surface Area

47.511

Acid Dissociation Constant (pKa)

14.51

Base Dissociation Constant (pKb)

9.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.52

T160-0424 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T160-0424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T160-0424?
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What is the minimum amount of T160-0424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T160-0424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T160-0424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T160-0424 available by request