T160-0670 Screening compound: 4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)-1-(propane-1-sulfonyl)piperidine

T160-0670 Screening compound: 4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)-1-(propane-1-sulfonyl)piperidine
T160-0670 Screening compound: 4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)-1-(propane-1-sulfonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound T160-0670
4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)-1-(propane-1-sulfonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T160-0670

Molecular Formula

C20H28FN3O2S (C20 H28 FN3 O2 S)

Compound Name

4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)-1-(propane-1-sulfonyl)piperidine

IUPAC name

4-({1-[(4-fluorophenyl)methyl]-5-methyl-1H-imidazol-2-yl}methyl)-1-(propane-1-sulfonyl)piperidine

SMILES

CCCS(N1CCC(Cc2ncc(C)n2Cc(cc2)ccc2F)CC1)(=O)=O

InChI

InChI=1S/C20H28FN3O2S/c1-3-12-27(25,26)23-10-8-17(9-11-23)13-20-22-14-16(2)24(20)15-18-4-6-19(21)7-5-18/h4-7,14,17H,3,8-13,15H2,1-2H3

InChI Key

GTVIPLQZLASCRQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD30467952

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.412

Distribution Coefficient, logD

2.171

Water Solubility, LogSw

-3.40

Polar Surface Area

44.005

Acid Dissociation Constant (pKa)

22.48

Base Dissociation Constant (pKb)

8.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.00

T160-0670 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T160-0670 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T160-0670?
Check Price and Availability of T160-0670, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T160-0670 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T160-0670
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T160-0670
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T160-0670 available by request