T167-1486 Screening compound: N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2,5-dimethylbenzamide

T167-1486 Screening compound: N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2,5-dimethylbenzamide
T167-1486 Screening compound: N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2,5-dimethylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T167-1486
N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2,5-dimethylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T167-1486

Molecular Formula

C22H28N4O2 (C22 H28 N4 O2)

Compound Name

N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2,5-dimethylbenzamide

IUPAC name

N-{1-[1-(cyclopropylmethyl)-6-oxo-16-dihydropyridazin-4-yl]piperidin-4-yl}-25-dimethylbenzamide

SMILES

Cc1cc(C(NC(CC2)CCN2C(C=NN2CC3CC3)=CC2=O)=O)c(C)cc1

InChI

InChI=1S/C22H28N4O2/c1-15-3-4-16(2)20(11-15)22(28)24-18-7-9-25(10-8-18)19-12-21(27)26(23-13-19)14-17-5-6-17/h3-4,11-13,17-18H,5-10,14H2,1-2H3,(H,24,28)

InChI Key

QRSIRDFABWGVPU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29002937

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.262

Distribution Coefficient, logD

3.252

Water Solubility, LogSw

-3.35

Polar Surface Area

56.963

Acid Dissociation Constant (pKa)

13.75

Base Dissociation Constant (pKb)

4.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

T167-1486 in Drug Discovery

Included in Screening Libraries

Bromodomain Modulators Library (5801 compounds)

CNS Targets (44014 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T167-1486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T167-1486?
Check Price and Availability of T167-1486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T167-1486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T167-1486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T167-1486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T167-1486 available by request