T368-1384 Screening compound: 2-methoxy-5-{3-[2-(thiophen-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}pyridine

T368-1384 Screening compound: 2-methoxy-5-{3-[2-(thiophen-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}pyridine
T368-1384 Screening compound: 2-methoxy-5-{3-[2-(thiophen-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-1384
2-methoxy-5-{3-[2-(thiophen-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-1384

Molecular Formula

C21H19N5O2S (C21 H19 N5 O2 S)

Compound Name

2-methoxy-5-{3-[2-(thiophen-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}pyridine

IUPAC name

2-methoxy-5-{3-[2-(thiophen-3-yl)-3H-imidazo[45-b]pyridin-3-yl]pyrrolidine-1-carbonyl}pyridine

SMILES

COc(cc1)ncc1C(N(CC1)CC1n1c(nccc2)c2nc1-c1cscc1)=O

InChI

InChI=1S/C21H19N5O2S/c1-28-18-5-4-14(11-23-18)21(27)25-9-6-16(12-25)26-19(15-7-10-29-13-15)24-17-3-2-8-22-20(17)26/h2-5,7-8,10-11,13,16H,6,9,12H2,1H3/t16-/m0/s1

InChI Key

RTKPLFQUELKRLK-INIZCTEOSA-N

MDL Number (MFCD)

MFCD29023282

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.675

Distribution Coefficient, logD

2.675

Water Solubility, LogSw

-2.56

Polar Surface Area

54.734

Acid Dissociation Constant (pKa)

17.21

Base Dissociation Constant (pKb)

2.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

T368-1384 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-1384 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-1384?
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What is the minimum amount of T368-1384 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-1384
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-1384
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-1384 available by request