T368-3080 Screening compound: 8-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]quinoline

T368-3080 Screening compound: 8-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]quinoline
T368-3080 Screening compound: 8-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]quinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-3080
8-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]quinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-3080

Molecular Formula

C22H23N5O2S (C22 H23 N5 O2 S)

Compound Name

8-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]quinoline

IUPAC name

8-[(3-{2-propyl-3H-imidazo[45-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]quinoline

SMILES

CCCc1nc2cccnc2n1C(CC1)CN1S(c1cccc2cccnc12)(=O)=O

InChI

InChI=1S/C22H23N5O2S/c1-2-6-20-25-18-9-5-13-24-22(18)27(20)17-11-14-26(15-17)30(28,29)19-10-3-7-16-8-4-12-23-21(16)19/h3-5,7-10,12-13,17H,2,6,11,14-15H2,1H3/t17-/m1/s1

InChI Key

UUIDFKXTVMDWGS-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD28121222

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.856

Distribution Coefficient, logD

2.856

Water Solubility, LogSw

-3.13

Polar Surface Area

62.978

Acid Dissociation Constant (pKa)

18.63

Base Dissociation Constant (pKb)

3.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

T368-3080 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-3080 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-3080?
Check Price and Availability of T368-3080, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-3080 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-3080
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-3080
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-3080 available by request