T387-0913 Screening compound: 4-{1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carbonyl}morpholine

T387-0913 Screening compound: 4-{1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carbonyl}morpholine
T387-0913 Screening compound: 4-{1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carbonyl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound T387-0913
4-{1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carbonyl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T387-0913

Molecular Formula

C20H22N6O2S (C20 H22 N6 O2 S)

Compound Name

4-{1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carbonyl}morpholine

IUPAC name

n/a

SMILES

O=C(C(CC1)CCN1c1nc2ccc(-c3cncnc3)nc2s1)N1CCOCC1

InChI

InChI=1S/C20H22N6O2S/c27-19(25-7-9-28-10-8-25)14-3-5-26(6-4-14)20-24-17-2-1-16(23-18(17)29-20)15-11-21-13-22-12-15/h1-2,11-14H,3-10H2

InChI Key

LWAFOMNZOKCJEV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619146

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.539

Distribution Coefficient, logD

1.101

Water Solubility, LogSw

-1.74

Polar Surface Area

67.235

Acid Dissociation Constant (pKa)

20.97

Base Dissociation Constant (pKb)

7.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

T387-0913 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T387-0913 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T387-0913?
Check Price and Availability of T387-0913, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T387-0913 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T387-0913
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T387-0913
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T387-0913 available by request