T424-0007 Screening compound: 5-{3-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-2,3-dihydropyridazin-3-one

T424-0007 Screening compound: 5-{3-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-2,3-dihydropyridazin-3-one
T424-0007 Screening compound: 5-{3-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-2,3-dihydropyridazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T424-0007
5-{3-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-2,3-dihydropyridazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T424-0007

Molecular Formula

C19H24N6O2 (C19 H24 N6 O2)

Compound Name

5-{3-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-2,3-dihydropyridazin-3-one

IUPAC name

5-{3-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-23-dihydropyridazin-3-one

SMILES

O=C(C(CCC1)CN1C(C=NN1)=CC1=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C19H24N6O2/c26-18-12-16(13-21-22-18)25-7-3-4-15(14-25)19(27)24-10-8-23(9-11-24)17-5-1-2-6-20-17/h1-2,5-6,12-13,15H,3-4,7-11,14H2,(H,22,26)/t15-/m0/s1

InChI Key

RSZTWRQLHMWFGK-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29022338

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.617

Distribution Coefficient, logD

1.608

Water Solubility, LogSw

-1.88

Polar Surface Area

70.522

Acid Dissociation Constant (pKa)

12.52

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.40

T424-0007 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T424-0007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T424-0007?
Check Price and Availability of T424-0007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T424-0007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T424-0007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T424-0007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T424-0007 available by request