T425-0518 Screening compound: ethyl 2-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}acetate

T425-0518 Screening compound: ethyl 2-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}acetate
T425-0518 Screening compound: ethyl 2-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound T425-0518
ethyl 2-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T425-0518

Molecular Formula

C22H25N5O4 (C22 H25 N5 O4)

Compound Name

ethyl 2-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}acetate

IUPAC name

ethyl 2-{4-[8-(4-methoxyphenyl)imidazo[12-a]pyrazine-2-carbonyl]piperazin-1-yl}acetate

SMILES

CCOC(CN(CC1)CCN1C(c1cn(ccnc2-c(cc3)ccc3OC)c2n1)=O)=O

InChI

InChI=1S/C22H25N5O4/c1-3-31-19(28)15-25-10-12-26(13-11-25)22(29)18-14-27-9-8-23-20(21(27)24-18)16-4-6-17(30-2)7-5-16/h4-9,14H,3,10-13,15H2,1-2H3

InChI Key

XDACGBACRHDPOH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29022711

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.506

Distribution Coefficient, logD

1.506

Water Solubility, LogSw

-1.89

Polar Surface Area

68.161

Acid Dissociation Constant (pKa)

24.38

Base Dissociation Constant (pKb)

4.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

T425-0518 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with T425-0518 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T425-0518?
Check Price and Availability of T425-0518, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T425-0518 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T425-0518
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T425-0518
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T425-0518 available by request