T425-0552 Screening compound: 3-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}propanenitrile

T425-0552 Screening compound: 3-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}propanenitrile
T425-0552 Screening compound: 3-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}propanenitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound T425-0552
3-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}propanenitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T425-0552

Molecular Formula

C21H22N6O2 (C21 H22 N6 O2)

Compound Name

3-{4-[8-(4-methoxyphenyl)imidazo[1,2-a]pyrazine-2-carbonyl]piperazin-1-yl}propanenitrile

IUPAC name

3-{4-[8-(4-methoxyphenyl)imidazo[12-a]pyrazine-2-carbonyl]piperazin-1-yl}propanenitrile

SMILES

COc(cc1)ccc1-c1nccn2c1nc(C(N1CCN(CCC#N)CC1)=O)c2

InChI

InChI=1S/C21H22N6O2/c1-29-17-5-3-16(4-6-17)19-20-24-18(15-27(20)10-8-23-19)21(28)26-13-11-25(12-14-26)9-2-7-22/h3-6,8,10,15H,2,9,11-14H2,1H3

InChI Key

UHLDOBSHVMAELY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29022720

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.060

Distribution Coefficient, logD

1.060

Water Solubility, LogSw

-1.58

Polar Surface Area

65.473

Acid Dissociation Constant (pKa)

22.02

Base Dissociation Constant (pKb)

4.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

T425-0552 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with T425-0552 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T425-0552?
Check Price and Availability of T425-0552, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T425-0552 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T425-0552
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T425-0552
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T425-0552 available by request