T480-0363 Screening compound: 4-methyl-1-[5-methyl-2-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-yl]piperidine

T480-0363 Screening compound: 4-methyl-1-[5-methyl-2-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-yl]piperidine
T480-0363 Screening compound: 4-methyl-1-[5-methyl-2-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound T480-0363
4-methyl-1-[5-methyl-2-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T480-0363

Molecular Formula

C18H24N4OS (C18 H24 N4 OS)

Compound Name

4-methyl-1-[5-methyl-2-(pyrrolidine-1-carbonyl)thieno[3,4-d]pyrimidin-4-yl]piperidine

IUPAC name

4-methyl-1-[5-methyl-2-(pyrrolidine-1-carbonyl)thieno[34-d]pyrimidin-4-yl]piperidine

SMILES

CC(CC1)CCN1c1nc(C(N2CCCC2)=O)nc2csc(C)c12

InChI

InChI=1S/C18H24N4OS/c1-12-5-9-21(10-6-12)17-15-13(2)24-11-14(15)19-16(20-17)18(23)22-7-3-4-8-22/h11-12H,3-10H2,1-2H3

InChI Key

SVOICWLLUXNJJK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29028236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.058

Distribution Coefficient, logD

4.058

Water Solubility, LogSw

-4.13

Polar Surface Area

39.943

Acid Dissociation Constant (pKa)

21.66

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.11

T480-0363 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T480-0363 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T480-0363?
Check Price and Availability of T480-0363, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T480-0363 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T480-0363
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T480-0363
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T480-0363 available by request