T480-0554 Screening compound: 4-[2-(4-cyclopentylpiperazine-1-carbonyl)-5-methylthieno[3,4-d]pyrimidin-4-yl]morpholine

T480-0554 Screening compound: 4-[2-(4-cyclopentylpiperazine-1-carbonyl)-5-methylthieno[3,4-d]pyrimidin-4-yl]morpholine
T480-0554 Screening compound: 4-[2-(4-cyclopentylpiperazine-1-carbonyl)-5-methylthieno[3,4-d]pyrimidin-4-yl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound T480-0554
4-[2-(4-cyclopentylpiperazine-1-carbonyl)-5-methylthieno[3,4-d]pyrimidin-4-yl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T480-0554

Molecular Formula

C21H29N5O2S (C21 H29 N5 O2 S)

Compound Name

4-[2-(4-cyclopentylpiperazine-1-carbonyl)-5-methylthieno[3,4-d]pyrimidin-4-yl]morpholine

IUPAC name

4-[2-(4-cyclopentylpiperazine-1-carbonyl)-5-methylthieno[34-d]pyrimidin-4-yl]morpholine

SMILES

Cc1c2c(N3CCOCC3)nc(C(N(CC3)CCN3C3CCCC3)=O)nc2cs1

InChI

InChI=1S/C21H29N5O2S/c1-15-18-17(14-29-15)22-19(23-20(18)25-10-12-28-13-11-25)21(27)26-8-6-24(7-9-26)16-4-2-3-5-16/h14,16H,2-13H2,1H3

InChI Key

IYAJPPSLLFYODZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024426

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.967

Distribution Coefficient, logD

2.704

Water Solubility, LogSw

-3.08

Polar Surface Area

50.945

Acid Dissociation Constant (pKa)

22.34

Base Dissociation Constant (pKb)

7.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.70

T480-0554 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Others
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with T480-0554 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T480-0554?
Check Price and Availability of T480-0554, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T480-0554 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T480-0554
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T480-0554
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T480-0554 available by request