T499-0311 Screening compound: cyclobutyl[3-(3-propyl-3H-imidazo[4,5-b]pyridin-2-yl)-1-pyrrolidinyl]methanone

T499-0311 Screening compound: cyclobutyl[3-(3-propyl-3H-imidazo[4,5-b]pyridin-2-yl)-1-pyrrolidinyl]methanone
T499-0311 Screening compound: cyclobutyl[3-(3-propyl-3H-imidazo[4,5-b]pyridin-2-yl)-1-pyrrolidinyl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound T499-0311
cyclobutyl[3-(3-propyl-3H-imidazo[4,5-b]pyridin-2-yl)-1-pyrrolidinyl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T499-0311

Molecular Formula

C18H24N4O (C18 H24 N4 O)

Compound Name

cyclobutyl[3-(3-propyl-3H-imidazo[4,5-b]pyridin-2-yl)-1-pyrrolidinyl]methanone

IUPAC name

1-cyclobutanecarbonyl-3-{3-propyl-3H-imidazo[45-b]pyridin-2-yl}pyrrolidine

SMILES

CCCn1c(nccc2)c2nc1C(CC1)CN1C(C1CCC1)=O

InChI

InChI=1S/C18H24N4O/c1-2-10-22-16(20-15-7-4-9-19-17(15)22)14-8-11-21(12-14)18(23)13-5-3-6-13/h4,7,9,13-14H,2-3,5-6,8,10-12H2,1H3/t14-/m1/s1

InChI Key

UDOFPAKPCCQWNG-CQSZACIVSA-N

MDL Number (MFCD)

MFCD27622156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

312.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.383

Distribution Coefficient, logD

2.383

Water Solubility, LogSw

-2.35

Polar Surface Area

37.523

Acid Dissociation Constant (pKa)

21.95

Base Dissociation Constant (pKb)

3.66

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.11

T499-0311 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with T499-0311 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T499-0311?
Check Price and Availability of T499-0311, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T499-0311 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T499-0311
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T499-0311
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T499-0311 available by request