T501-1324 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidin-1-yl)propan-1-one

T501-1324 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidin-1-yl)propan-1-one
T501-1324 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidin-1-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T501-1324
3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidin-1-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T501-1324

Molecular Formula

C25H33N5O4S (C25 H33 N5 O4 S)

Compound Name

3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidin-1-yl)propan-1-one

IUPAC name

3-[(1-acetyl-23-dihydro-1H-indol-5-yl)sulfonyl]-1-(3-{[4-(cyclopropylmethyl)-4H-124-triazol-3-yl]methyl}piperidin-1-yl)propan-1-one

SMILES

CC(N(CC1)c(cc2)c1cc2S(CCC(N1CC(Cc2nncn2CC2CC2)CCC1)=O)(=O)=O)=O

InChI

InChI=1S/C25H33N5O4S/c1-18(31)30-11-8-21-14-22(6-7-23(21)30)35(33,34)12-9-25(32)28-10-2-3-20(16-28)13-24-27-26-17-29(24)15-19-4-5-19/h6-7,14,17,19-20H,2-5,8-13,15-16H2,1H3/t20-/m1/s1

InChI Key

NJFTZOQABWIMOW-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD30467996

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.63

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.999

Distribution Coefficient, logD

0.999

Water Solubility, LogSw

-2.40

Polar Surface Area

87.331

Acid Dissociation Constant (pKa)

21.08

Base Dissociation Constant (pKb)

2.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

60.00

T501-1324 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with T501-1324 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T501-1324?
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What is the minimum amount of T501-1324 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T501-1324
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T501-1324
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T501-1324 available by request